Dysregulation of Blood-Brain Barrier and Exacerbated Inflammatory Response in Cx47-Deficient Mice after Induction of EAE

Induction of experimental autoimmune encephalomyelitis (EAE), an animal model of multiple sclerosis (MS), in connexin 32 (Cx32) or Cx47 knockout (KO) mice with deficiency in oligodendrocyte gap junctions (GJs) results in a more severe disease course. In particular, Cx47 KO EAE mice experience an ear...

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Detalles Bibliográficos
Autores principales: Stavropoulos, Filippos, Georgiou, Elena, Sargiannidou, Irene, Kleopa, Kleopas A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8308522/
https://www.ncbi.nlm.nih.gov/pubmed/34203192
http://dx.doi.org/10.3390/ph14070621

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8308522/
https://www.ncbi.nlm.nih.gov/pubmed/34203192
http://dx.doi.org/10.3390/ph14070621

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