Interaction between DNA, Albumin and Apo-Transferrin and Iridium(III) Complexes with Phosphines Derived from Fluoroquinolones as a Potent Anticancer Drug

A group of cytotoxic half-sandwich iridium(III) complexes with aminomethyl(diphenyl)phosphine derived from fluoroquinolone antibiotics exhibit the ability to (i) accumulate in the nucleus, (ii) induce apoptosis, (iii) activate caspase-3/7 activity, (iv) induce the changes in cell cycle leading to G2...

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Detalles Bibliográficos
Autores principales: Kozieł, Sandra Amanda, Lesiów, Monika Katarzyna, Wojtala, Daria, Dyguda-Kazimierowicz, Edyta, Bieńko, Dariusz, Komarnicka, Urszula Katarzyna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8308524/
https://www.ncbi.nlm.nih.gov/pubmed/34358111
http://dx.doi.org/10.3390/ph14070685

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8308524/
https://www.ncbi.nlm.nih.gov/pubmed/34358111
http://dx.doi.org/10.3390/ph14070685

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