CPPs to the Test: Effects on Binding, Uptake and Biodistribution of a Tumor Targeting Nanobody

Nanobodies are well-established targeting ligands for molecular imaging and therapy. Their short circulation time enables early imaging and reduces systemic radiation exposure. However, shorter circulation time leads to lower tracer accumulation in the target tissue. Cell-penetrating peptides (CPPs)...

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Detalles Bibliográficos
Autores principales: Collado Camps, Estel, van Lith, Sanne A. M., Frielink, Cathelijne, Lankhof, Jordi, Dijkgraaf, Ingrid, Gotthardt, Martin, Brock, Roland
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8308549/
https://www.ncbi.nlm.nih.gov/pubmed/34201507
http://dx.doi.org/10.3390/ph14070602

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8308549/
https://www.ncbi.nlm.nih.gov/pubmed/34201507
http://dx.doi.org/10.3390/ph14070602

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