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Pharmacokinetic Properties of the Novel Synthetic Cannabinoid 5F-APINAC and Its Influence on Metabolites Associated with Neurotransmission in Rabbit Plasma

The strong psychoactive effects of synthetic cannabinoids raise the need for the deeper studying of their neurometabolic effects. The pharmacokinetic properties of 5F-APINAC and its influence on metabolomics profiles associated with neurotransmission were investigated in rabbit plasma. Twelve rabbit...

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Detalles Bibliográficos
Autores principales: Shestakova, Ksenia M., Mesonzhnik, Natalia V., Markin, Pavel A., Moskaleva, Natalia E., Nedorubov, Andrey A., Brito, Alex, Appolonova, Elizaveta G., Kuznetsov, Roman M., Bochkareva, Natalia L., Kukharenko, Alexey, Lyundup, Alexey V., Tagliaro, Franco, Appolonova, Svetlana A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8308683/
https://www.ncbi.nlm.nih.gov/pubmed/34358094
http://dx.doi.org/10.3390/ph14070668