CCR5 Antagonist Maraviroc Inhibits Acute Exacerbation of Lung Inflammation Triggered by Influenza Virus in Cigarette Smoke-Exposed Mice

Influenza A virus (IAV) infection is a common cause of acute exacerbations of chronic obstructive pulmonary disease (AECOPD). Since macrophage inflammatory protein 1 α, a chemokine that acts through CC-chemokine receptor (CCR)-5, appears elevated in COPD patients’ airways, we evaluated whether CCR5...

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Detalles Bibliográficos
Autores principales: Ferrero, Maximiliano Ruben, Garcia, Cristiana Couto, Dutra de Almeida, Marcella, Torres Braz da Silva, Jullian, Bianchi Reis Insuela, Daniella, Teixeira Ferreira, Tatiana Paula, de Sá Coutinho, Diego, Trindade de Azevedo, Carolina, Machado Rodrigues e Silva, Patrícia, Martins, Marco Aurélio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8308708/
https://www.ncbi.nlm.nih.gov/pubmed/34203121
http://dx.doi.org/10.3390/ph14070620

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8308708/
https://www.ncbi.nlm.nih.gov/pubmed/34203121
http://dx.doi.org/10.3390/ph14070620

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