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CCR5 Antagonist Maraviroc Inhibits Acute Exacerbation of Lung Inflammation Triggered by Influenza Virus in Cigarette Smoke-Exposed Mice
Influenza A virus (IAV) infection is a common cause of acute exacerbations of chronic obstructive pulmonary disease (AECOPD). Since macrophage inflammatory protein 1 α, a chemokine that acts through CC-chemokine receptor (CCR)-5, appears elevated in COPD patients’ airways, we evaluated whether CCR5...
Autores principales: | Ferrero, Maximiliano Ruben, Garcia, Cristiana Couto, Dutra de Almeida, Marcella, Torres Braz da Silva, Jullian, Bianchi Reis Insuela, Daniella, Teixeira Ferreira, Tatiana Paula, de Sá Coutinho, Diego, Trindade de Azevedo, Carolina, Machado Rodrigues e Silva, Patrícia, Martins, Marco Aurélio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8308708/ https://www.ncbi.nlm.nih.gov/pubmed/34203121 http://dx.doi.org/10.3390/ph14070620 |
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