An Effective and Safe Enkephalin Analog for Antinociception

Opioids account for 69,000 overdose deaths per annum worldwide and cause serious side effects. Safer analgesics are urgently needed. The endogenous opioid peptide Leu-Enkephalin (Leu-ENK) is ineffective when introduced peripherally due to poor stability and limited membrane permeability. We develope...

Descripción completa

Detalles Bibliográficos
Autores principales: Viswanadham, K. K. DurgaRao, Böttger, Roland, Hohenwarter, Lukas, Nguyen, Anne, Rouhollahi, Elham, Smith, Alexander, Tsai, Yi-Hsuan, Chang, Yuan-Yu, Ortiz, Christopher Llynard, Yang, Lee-Wei, Jimenez, Liliana, Li, Siyuan, Hur, Chan, Li, Shyh-Dar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8308721/
https://www.ncbi.nlm.nih.gov/pubmed/34206631
http://dx.doi.org/10.3390/pharmaceutics13070927

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8308721/
https://www.ncbi.nlm.nih.gov/pubmed/34206631
http://dx.doi.org/10.3390/pharmaceutics13070927

Ejemplares similares