Investigating In Vitro and Ex Vivo Properties of Artemether/Lumefantrine Double-Fixed Dose Combination Lipid Matrix Tablets Prepared by Hot Fusion

Highly lipophilic antimalarial drugs, artemether and lumefantrine, whilst an effective fixed-dose combination treatment to lower the malarial disease burden, are therapeutically hindered by low aqueous solubility and varied bioavailability. This work investigates the plausibility of directly compres...

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Detalles Bibliográficos
Autores principales: Wilkins, Christi A., du Plessis, Lissinda H., Viljoen, Joe M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8308765/
https://www.ncbi.nlm.nih.gov/pubmed/34206248
http://dx.doi.org/10.3390/pharmaceutics13070922

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8308765/
https://www.ncbi.nlm.nih.gov/pubmed/34206248
http://dx.doi.org/10.3390/pharmaceutics13070922

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