Ac-EAZY! Towards GMP-Compliant Module Syntheses of (225)Ac-Labeled Peptides for Clinical Application

The application of (225)Ac (half-life T(1/2) = 9.92 d) dramatically reduces the activity used for peptide receptor radionuclide therapy by a factor of 1000 in comparison to (90)Y, (177)Lu or (188)Re while maintaining the therapeutic outcome. Additionally, the range of alpha particles of (225)Ac and...

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Detalles Bibliográficos
Autores principales: Pretze, Marc, Kunkel, Falk, Runge, Roswitha, Freudenberg, Robert, Braune, Anja, Hartmann, Holger, Schwarz, Uwe, Brogsitter, Claudia, Kotzerke, Jörg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8308848/
https://www.ncbi.nlm.nih.gov/pubmed/34358076
http://dx.doi.org/10.3390/ph14070652

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8308848/
https://www.ncbi.nlm.nih.gov/pubmed/34358076
http://dx.doi.org/10.3390/ph14070652

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