New (Iso)quinolinyl-pyridine-2,6-dicarboxamide G-Quadruplex Stabilizers. A Structure-Activity Relationship Study

G-quadruplex (G4)-interactive small molecules have a wide range of potential applications, not only as drugs, but also as sensors of quadruplex structures. The purpose of this work is the synthesis of analogues of the bis-methylquinolinium-pyridine-2,6-dicarboxamide G4 ligand 360A, to identify relev...

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Detalles Bibliográficos
Autores principales: Cadoni, Enrico, Magalhães, Pedro R., Emídio, Rita M., Mendes, Eduarda, Vítor, Jorge, Carvalho, Josué, Cruz, Carla, Victor, Bruno L., Paulo, Alexandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8308870/
https://www.ncbi.nlm.nih.gov/pubmed/34358095
http://dx.doi.org/10.3390/ph14070669

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8308870/
https://www.ncbi.nlm.nih.gov/pubmed/34358095
http://dx.doi.org/10.3390/ph14070669

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