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Variations in the Abortive HIV-1 RNA Hairpin Do Not Impede Viral Sensing and Innate Immune Responses

The highly conserved trans-acting response element (TAR) present in the RNA genome of human immunodeficiency virus 1 (HIV-1) is a stably folded hairpin structure involved in viral replication. However, TAR is also sensed by viral sensors, leading to antiviral immunity. While high variation in the TA...

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Detalles Bibliográficos
Autores principales: Stunnenberg, Melissa, van Hamme, John L., Das, Atze T., Berkhout, Ben, Geijtenbeek, Teunis B. H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8308900/
https://www.ncbi.nlm.nih.gov/pubmed/34358047
http://dx.doi.org/10.3390/pathogens10070897