Development of Machine Learning Models for Accurately Predicting and Ranking the Activity of Lead Molecules to Inhibit PRC2 Dependent Cancer

Disruption of epigenetic processes to eradicate tumor cells is among the most promising interventions for cancer control. EZH2 (Enhancer of zeste homolog 2), a catalytic component of polycomb repressive complex 2 (PRC2), methylates lysine 27 of histone H3 to promote transcriptional silencing and is...

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Detalles Bibliográficos
Autores principales: Danishuddin, Kumar, Vikas, Parate, Shraddha, Bahuguna, Ashutosh, Lee, Gihwan, Kim, Myeong Ok, Lee, Keun Woo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8308948/
https://www.ncbi.nlm.nih.gov/pubmed/34358125
http://dx.doi.org/10.3390/ph14070699

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8308948/
https://www.ncbi.nlm.nih.gov/pubmed/34358125
http://dx.doi.org/10.3390/ph14070699

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