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Anti-Fn14 Antibody-Conjugated Nanoparticles Display Membrane TWEAK-Like Agonism (†)

Conventional bivalent IgG antibodies targeting a subgroup of receptors of the TNF superfamily (TNFSF) including fibroblast growth factor-inducible 14 (anti-Fn14) typically display no or only very limited agonistic activity on their own and can only trigger receptor signaling by crosslinking or when...

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Detalles Bibliográficos
Autores principales: Aido, Ahmed, Zaitseva, Olena, Wajant, Harald, Buzgo, Matej, Simaite, Aiva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8308961/
https://www.ncbi.nlm.nih.gov/pubmed/34371763
http://dx.doi.org/10.3390/pharmaceutics13071072