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Anti-Fn14 Antibody-Conjugated Nanoparticles Display Membrane TWEAK-Like Agonism (†)
Conventional bivalent IgG antibodies targeting a subgroup of receptors of the TNF superfamily (TNFSF) including fibroblast growth factor-inducible 14 (anti-Fn14) typically display no or only very limited agonistic activity on their own and can only trigger receptor signaling by crosslinking or when...
Autores principales: | Aido, Ahmed, Zaitseva, Olena, Wajant, Harald, Buzgo, Matej, Simaite, Aiva |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8308961/ https://www.ncbi.nlm.nih.gov/pubmed/34371763 http://dx.doi.org/10.3390/pharmaceutics13071072 |
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