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Impact of Matrix Surface Area on Griseofulvin Release from Extrudates Prepared via Nanoextrusion
We aimed to examine the impact of milling of extrudates prepared via nanoextrusion and the resulting matrix surface area of the particles on griseofulvin (GF, a model poorly soluble drug) release during in vitro dissolution. Wet-milled GF nanosuspensions containing a polymer (Sol: Soluplus(®), Kol:...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8308970/ https://www.ncbi.nlm.nih.gov/pubmed/34371728 http://dx.doi.org/10.3390/pharmaceutics13071036 |