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Impact of Matrix Surface Area on Griseofulvin Release from Extrudates Prepared via Nanoextrusion

We aimed to examine the impact of milling of extrudates prepared via nanoextrusion and the resulting matrix surface area of the particles on griseofulvin (GF, a model poorly soluble drug) release during in vitro dissolution. Wet-milled GF nanosuspensions containing a polymer (Sol: Soluplus(®), Kol:...

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Detalles Bibliográficos
Autores principales:	Li, Meng, Furey, Casey, Skros, Jeffrey, Xu, Olivia, Rahman, Mahbubur, Azad, Mohammad, Dave, Rajesh, Bilgili, Ecevit
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8308970/ https://www.ncbi.nlm.nih.gov/pubmed/34371728 http://dx.doi.org/10.3390/pharmaceutics13071036

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