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Intracellular Routing and Recognition of Lipid-Based mRNA Nanoparticles

Messenger RNA (mRNA) is being extensively used in gene therapy and vaccination due to its safety over DNA, in the following ways: its lack of integration risk, cytoplasmic expression, and transient expression compatible with fine regulations. However, clinical applications of mRNA are limited by its...

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Detalles Bibliográficos
Autores principales: Delehedde, Christophe, Even, Luc, Midoux, Patrick, Pichon, Chantal, Perche, Federico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8308975/
https://www.ncbi.nlm.nih.gov/pubmed/34202584
http://dx.doi.org/10.3390/pharmaceutics13070945