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Intracellular Routing and Recognition of Lipid-Based mRNA Nanoparticles
Messenger RNA (mRNA) is being extensively used in gene therapy and vaccination due to its safety over DNA, in the following ways: its lack of integration risk, cytoplasmic expression, and transient expression compatible with fine regulations. However, clinical applications of mRNA are limited by its...
Autores principales: | Delehedde, Christophe, Even, Luc, Midoux, Patrick, Pichon, Chantal, Perche, Federico |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8308975/ https://www.ncbi.nlm.nih.gov/pubmed/34202584 http://dx.doi.org/10.3390/pharmaceutics13070945 |
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