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Particle-Scale Modeling to Understand Liquid Distribution in Twin-Screw Wet Granulation
Experimental characterization of solid-liquid mixing for a high shear wet granulation process in a twin-screw granulator (TSG) is very challenging. This is due to the opacity of the multiphase system and high-speed processing. In this study, discrete element method (DEM) based simulations are perfor...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8308998/ https://www.ncbi.nlm.nih.gov/pubmed/34206609 http://dx.doi.org/10.3390/pharmaceutics13070928 |