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Optimization of Layered Dissolving Microneedle for Sustained Drug Delivery Using Heat-Melted Poly(Lactic-Co-glycolic Acid)

Dissolving microneedles (DMNs) have been used as an alternative drug delivery system to deliver therapeutics across the skin barrier in a painless manner. In this study, we propose a novel heat-melting method for the fabrication of hydrophobic poly(lactic-co-glycolic acid) (PLGA) DMNs, without the u...

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Detalles Bibliográficos
Autores principales: Lee, Chisong, Kim, Jinkyung, Um, Daniel Junmin, Kim, Youseong, Min, Hye Su, Shin, Jiwoo, Nam, Jee Hye, Kang, Geonwoo, Jang, Mingyu, Yang, Huisuk, Jung, Hyungil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8309023/
https://www.ncbi.nlm.nih.gov/pubmed/34371749
http://dx.doi.org/10.3390/pharmaceutics13071058