Cargando…

Optimization of Layered Dissolving Microneedle for Sustained Drug Delivery Using Heat-Melted Poly(Lactic-Co-glycolic Acid)

Dissolving microneedles (DMNs) have been used as an alternative drug delivery system to deliver therapeutics across the skin barrier in a painless manner. In this study, we propose a novel heat-melting method for the fabrication of hydrophobic poly(lactic-co-glycolic acid) (PLGA) DMNs, without the u...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lee, Chisong, Kim, Jinkyung, Um, Daniel Junmin, Kim, Youseong, Min, Hye Su, Shin, Jiwoo, Nam, Jee Hye, Kang, Geonwoo, Jang, Mingyu, Yang, Huisuk, Jung, Hyungil
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8309023/ https://www.ncbi.nlm.nih.gov/pubmed/34371749 http://dx.doi.org/10.3390/pharmaceutics13071058

Ejemplares similares

Solvent-Free Polycaprolactone Dissolving Microneedles Generated via the Thermal Melting Method for the Sustained Release of Capsaicin
por: Eum, Jaehong, et al.
Publicado: (2021)

Development of Lidocaine-Loaded Dissolving Microneedle for Rapid and Efficient Local Anesthesia
por: Yang, Huisuk, et al.
Publicado: (2020)

Development of Clinical Weekly-Dose Teriparatide Acetate Encapsulated Dissolving Microneedle Patch for Efficient Treatment of Osteoporosis
por: Sim, Jeeho, et al.
Publicado: (2022)

Film-trigger applicator (FTA) for improved skin penetration of microneedle using punching force of carboxymethyl cellulose film acting as a microneedle applicator
por: Kim, Youseong, et al.
Publicado: (2022)

The Troy Microneedle: A Rapidly Separating, Dissolving Microneedle Formed by Cyclic Contact and Drying on the Pillar (CCDP)
por: Kim, Miroo, et al.
Publicado: (2015)

Tissue Interlocking Dissolving Microneedles for Accurate and Efficient Transdermal Delivery of Biomolecules
por: Fakhraei Lahiji, Shayan, et al.
Publicado: (2019)

Scalp Micro-Pigmentation via Transcutaneous Implantation of Flexible Tissue Interlocking Biodegradable Microneedles
por: Fakhraei Lahiji, Shayan, et al.
Publicado: (2019)

Enhanced Micro-Channeling System via Dissolving Microneedle to Improve Transdermal Serum Delivery for Various Clinical Skincare Treatments
por: Sim, Jeeho, et al.
Publicado: (2022)

Rapidly Separable Micropillar Integrated Dissolving Microneedles
por: Jung, Chung-ryong, et al.
Publicado: (2020)

Dissolving Candlelit Microneedle for Chronic Inflammatory Skin Diseases
por: Ohn, Jungyoon, et al.
Publicado: (2021)

Dissolving Microneedles for Rapid and Painless Local Anesthesia
por: Lee, Byeong-Min, et al.
Publicado: (2020)

Exendin-4–encapsulated dissolving microneedle arrays for efficient treatment of type 2 diabetes
por: Fakhraei Lahiji, Shayan, et al.
Publicado: (2018)

Micro-Pillar Integrated Dissolving Microneedles for Enhanced Transdermal Drug Delivery
por: Lee, Seunghee, et al.
Publicado: (2019)

A patchless dissolving microneedle delivery system enabling rapid and efficient transdermal drug delivery
por: Lahiji, Shayan F., et al.
Publicado: (2015)

Pharmacokinetic Evaluation of a Novel Donepezil-Loaded Dissolving Microneedle Patch in Rats
por: Rehman, Naveed Ur, et al.
Publicado: (2021)

Nanostructured lipid carrier-loaded hyaluronic acid microneedles for controlled dermal delivery of a lipophilic molecule
por: Lee, Sang Gon, et al.
Publicado: (2013)

Dissolving Microneedle Patches for Dermal Vaccination
por: Leone, M., et al.
Publicado: (2017)

The Progress in the Application of Dissolving Microneedles in Biomedicine
por: Yu, Xueqing, et al.
Publicado: (2023)

Melt Rheology and Mechanical Characteristics of Poly(Lactic Acid)/Alkylated Graphene Oxide Nanocomposites
por: Park, In Hye, et al.
Publicado: (2020)

Dissolving microneedles delivering cancer cell membrane coated nanoparticles for cancer immunotherapy
por: Park, Wonchan, et al.
Publicado: (2021)

Properties of Poly (Lactic-co-Glycolic Acid) and Progress of Poly (Lactic-co-Glycolic Acid)-Based Biodegradable Materials in Biomedical Research
por: Lu, Yue, et al.
Publicado: (2023)

Preparation and Characterization of Poly(Lactic Acid)/Poly (ethylene glycol)-Poly(propyl glycol)-Poly(ethylene glycol) Blended Nanofiber Membranes for Fog Collection
por: Aijaz, Muhammad Omer, et al.
Publicado: (2022)

Peptide delivery with poly(ethylene glycol) diacrylate microneedles through swelling effect
por: Liu, Shiying, et al.
Publicado: (2017)

Dissolving Polymer Microneedle Patches for Influenza Vaccination
por: Sullivan, Sean P., et al.
Publicado: (2010)

Dissolving Microneedles for Intradermal Vaccination against Shigellosis
por: Pastor, Yadira, et al.
Publicado: (2019)

Dissolving Polymer Microneedles for Transdermal Delivery of Insulin
por: Zhang, Na, et al.
Publicado: (2021)

Bioimaging of Dissolvable Microneedle Arrays: Challenges and Opportunities
por: Wang, Yanni, et al.
Publicado: (2022)

Role of Electrospinning Parameters on Poly(Lactic-co-Glycolic Acid) and Poly(Caprolactone-co-Glycolic acid) Membranes
por: Herrero-Herrero, María, et al.
Publicado: (2021)

Enhanced anti-tumor immunotherapy by dissolving microneedle patch loaded ovalbumin
por: Lee, Sung-Ju, et al.
Publicado: (2019)

Review on the Degradation of Poly(lactic acid) during Melt Processing
por: Velghe, Ineke, et al.
Publicado: (2023)

Technology update: dissolvable microneedle patches for vaccine delivery
por: Rodgers, Aoife M, et al.
Publicado: (2019)

Deferasirox Nanosuspension Loaded Dissolving Microneedles for Intradermal Delivery
por: Faizi, Hafsa Shahid, et al.
Publicado: (2022)

Dissolvable polymeric microneedles loaded with aspirin for antiplatelet aggregation
por: Wang, Baorui, et al.
Publicado: (2023)

Design and Evaluation of Dissolvable Microneedles for Treating Atopic Dermatitis
por: Ben David, Noa, et al.
Publicado: (2023)

Polyhydroxyalkanoate Decelerates the Release of Paclitaxel from Poly(lactic-co-glycolic acid) Nanoparticles
por: Lee, Si Yeong, et al.
Publicado: (2022)

Safety evaluation of poly(lactic-co-glycolic acid)/poly(lactic-acid) microspheres through intravitreal injection in rabbits
por: Rong, Xianfang, et al.
Publicado: (2014)

Preparation of Cylinder-Shaped Porous Sponges of Poly(L-lactic acid), Poly(DL-lactic-co-glycolic acid), and Poly(ε-caprolactone)
por: He, Xiaoming, et al.
Publicado: (2014)

Process–Property Relationships for Melt-Spun Poly(lactic acid) Yarn
por: Gajjar, Chirag R., et al.
Publicado: (2021)

Encapsulation of Amikacin into Microparticles Based on Low-Molecular-Weight Poly(lactic acid) and Poly(lactic acid-co-polyethylene glycol)
por: Glinka, Marta, et al.
Publicado: (2021)

Nanosuspension-Based Dissolving Microneedle Arrays for Intradermal Delivery of Curcumin
por: Abdelghany, Sharif, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_asslg3slub76fm7d2m6uitdl51