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Lipoplexes to Deliver Oligonucleotides in Gram-Positive and Gram-Negative Bacteria: Towards Treatment of Blood Infections

Bacterial resistance to antibiotics threatens the ability to treat life-threatening bloodstream infections. Oligonucleotides (ONs) composed of nucleic acid mimics (NAMs) able to inhibit essential genes can become an alternative to traditional antibiotics, as long as they are safely transported in hu...

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Detalles Bibliográficos
Autores principales: Pereira, Sara, Santos, Rita Sobral, Moreira, Luís, Guimarães, Nuno, Gomes, Mariana, Zhang, Heyang, Remaut, Katrien, Braeckmans, Kevin, De Smedt, Stefaan, Azevedo, Nuno Filipe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8309032/
https://www.ncbi.nlm.nih.gov/pubmed/34210111
http://dx.doi.org/10.3390/pharmaceutics13070989