Timing of Novel Drug 1A-116 to Circadian Rhythms Improves Therapeutic Effects against Glioblastoma

The Ras homologous family of small guanosine triphosphate-binding enzymes (GTPases) is critical for cell migration and proliferation. The novel drug 1A-116 blocks the interaction site of the Ras-related C3 botulinum toxin substrate 1 (RAC1) GTPase with some of its guanine exchange factors (GEFs), su...

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Detalles Bibliográficos
Autores principales: Trebucq, Laura Lucía, Cardama, Georgina Alexandra, Lorenzano Menna, Pablo, Golombek, Diego Andrés, Chiesa, Juan José, Marpegan, Luciano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8309043/
https://www.ncbi.nlm.nih.gov/pubmed/34371781
http://dx.doi.org/10.3390/pharmaceutics13071091

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8309043/
https://www.ncbi.nlm.nih.gov/pubmed/34371781
http://dx.doi.org/10.3390/pharmaceutics13071091

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