In Vitro Metabolism Study of Seongsanamide A in Human Liver Microsomes Using Non-Targeted Metabolomics and Feature-Based Molecular Networking

Seongsanamide A is a bicyclic peptide with an isodityrosine residue discovered in Bacillus safensis KCTC 12796BP which exhibits anti-allergic activity in vitro and in vivo without significant cytotoxicity. The purpose of this study was to elucidate the in vitro metabolic pathway and potential for dr...

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Detalles Bibliográficos
Autores principales: Wu, Zhexue, Kim, Geum Jin, Park, So-Young, Shon, Jong Cheol, Liu, Kwang-Hyeon, Choi, Hyukjae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8309059/
https://www.ncbi.nlm.nih.gov/pubmed/34371722
http://dx.doi.org/10.3390/pharmaceutics13071031

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8309059/
https://www.ncbi.nlm.nih.gov/pubmed/34371722
http://dx.doi.org/10.3390/pharmaceutics13071031

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