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Dual-Acting Zeta-Potential-Changing Micelles for Optimal Mucus Diffusion and Enhanced Cellular Uptake after Oral Delivery

Context: Overcoming the intestinal mucosal barrier can be a challenge in drug delivery. Nanoemulsions with negative zeta potentials can effectively permeate the mucus layer, but those with positive zeta potentials are better taken up by cells; a nanoemulsion with capricious zeta potential from negat...

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Detalles Bibliográficos
Autores principales: Malkawi, Ahmad, Alrabadi, Nasr, Kennedy, Ross Allan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8309066/
https://www.ncbi.nlm.nih.gov/pubmed/34199091
http://dx.doi.org/10.3390/pharmaceutics13070974