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Sulfasalazine Microparticles Targeting Macrophages for the Treatment of Inflammatory Diseases Affecting the Synovial Cavity

Rheumatoid arthritis (RA) is a chronic inflammatory disease with sulfasalazine (SSZ) extensively used for long-term treatment of both juvenile and adult RA. Its use is associated with adverse effects and toxicity due to its non-selective biodistribution. Macrophages play an important role in inflamm...

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Detalles Bibliográficos
Autores principales: Villa-Hermosilla, Monica-Carolina, Fernández-Carballido, Ana, Hurtado, Carolina, Barcia, Emilia, Montejo, Consuelo, Alonso, Mario, Negro, Sofia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8309090/
https://www.ncbi.nlm.nih.gov/pubmed/34202859
http://dx.doi.org/10.3390/pharmaceutics13070951