Second-Generation Antimitotics in Cancer Clinical Trials

Mitosis represents a promising target to block cancer cell proliferation. Classical antimitotics, mainly microtubule-targeting agents (MTAs), such as taxanes and vinca alkaloids, are amongst the most successful anticancer drugs. By disrupting microtubules, they activate the spindle assembly checkpoi...

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Detalles Bibliográficos
Autores principales: Novais, Pedro, Silva, Patrícia M. A., Amorim, Isabel, Bousbaa, Hassan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8309102/
https://www.ncbi.nlm.nih.gov/pubmed/34371703
http://dx.doi.org/10.3390/pharmaceutics13071011

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8309102/
https://www.ncbi.nlm.nih.gov/pubmed/34371703
http://dx.doi.org/10.3390/pharmaceutics13071011

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