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Second-Generation Antimitotics in Cancer Clinical Trials

Mitosis represents a promising target to block cancer cell proliferation. Classical antimitotics, mainly microtubule-targeting agents (MTAs), such as taxanes and vinca alkaloids, are amongst the most successful anticancer drugs. By disrupting microtubules, they activate the spindle assembly checkpoi...

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Detalles Bibliográficos
Autores principales:	Novais, Pedro, Silva, Patrícia M. A., Amorim, Isabel, Bousbaa, Hassan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8309102/ https://www.ncbi.nlm.nih.gov/pubmed/34371703 http://dx.doi.org/10.3390/pharmaceutics13071011

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