Repositioning of Tamoxifen in Surface-Modified Nanocapsules as a Promising Oral Treatment for Visceral Leishmaniasis

Standards of care for human visceral leishmaniasis (VL) are based on drugs used parenterally, and oral treatment options are urgently needed. In the present study, a repurposing strategy was used associating tamoxifen (TMX) with polyethylene glycol-block-polylactide nanocapsules (NC) and its anti-le...

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Detalles Bibliográficos
Autores principales: Silva, Débora Faria, Reis, Levi Eduardo Soares, Machado, Marina Guimarães Carvalho, Dophine, Douglas Daniel, de Andrade, Vinicius Roberto, de Lima, Wanderson Geraldo, Andrade, Margareth Spangler, Vilela, José Mário Carneiro, Reis, Alexandre Barbosa, Pound-Lana, Gwenaelle, Rezende, Simone Aparecida, Mosqueira, Vanessa Carla Furtado
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8309129/
https://www.ncbi.nlm.nih.gov/pubmed/34371752
http://dx.doi.org/10.3390/pharmaceutics13071061

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8309129/
https://www.ncbi.nlm.nih.gov/pubmed/34371752
http://dx.doi.org/10.3390/pharmaceutics13071061

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