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Kinetic and Microhydrodynamic Modeling of Fenofibrate Nanosuspension Production in a Wet Stirred Media Mill

This study examined the impact of stirrer speed and bead material loading on fenofibrate particle breakage during wet stirred media milling (WSMM) via three kinetic models and a microhydrodynamic model. Evolution of median particle size was tracked via laser diffraction during WSMM operating at 3000...

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Detalles Bibliográficos
Autores principales: Guner, Gulenay, Yilmaz, Dogacan, Bilgili, Ecevit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8309173/
https://www.ncbi.nlm.nih.gov/pubmed/34371746
http://dx.doi.org/10.3390/pharmaceutics13071055