In Vitro Metabolism of Donepezil in Liver Microsomes Using Non-Targeted Metabolomics

Donepezil is a reversible acetylcholinesterase inhibitor that is currently the most commonly prescribed drug for the treatment of Alzheimer’s disease. In general, donepezil is known as a safe and well-tolerated drug, and it was not associated with liver abnormalities in several clinical trials. Howe...

Descripción completa

Detalles Bibliográficos
Autores principales: Kim, Sin-Eun, Seo, Hyung-Ju, Jeong, Yeojin, Lee, Gyung-Min, Ji, Seung-Bae, Park, So-Young, Wu, Zhexue, Lee, Sangkyu, Kim, Sunghwan, Liu, Kwang-Hyeon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8309179/
https://www.ncbi.nlm.nih.gov/pubmed/34201744
http://dx.doi.org/10.3390/pharmaceutics13070936

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8309179/
https://www.ncbi.nlm.nih.gov/pubmed/34201744
http://dx.doi.org/10.3390/pharmaceutics13070936

Ejemplares similares