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In Vitro Metabolism of Donepezil in Liver Microsomes Using Non-Targeted Metabolomics

Donepezil is a reversible acetylcholinesterase inhibitor that is currently the most commonly prescribed drug for the treatment of Alzheimer’s disease. In general, donepezil is known as a safe and well-tolerated drug, and it was not associated with liver abnormalities in several clinical trials. Howe...

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Detalles Bibliográficos
Autores principales:	Kim, Sin-Eun, Seo, Hyung-Ju, Jeong, Yeojin, Lee, Gyung-Min, Ji, Seung-Bae, Park, So-Young, Wu, Zhexue, Lee, Sangkyu, Kim, Sunghwan, Liu, Kwang-Hyeon
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8309179/ https://www.ncbi.nlm.nih.gov/pubmed/34201744 http://dx.doi.org/10.3390/pharmaceutics13070936

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