Methotrexate-Loaded Gelatin and Polyvinyl Alcohol (Gel/PVA) Hydrogel as a pH-Sensitive Matrix

The aim was to formulate and evaluate Gel/PVA hydrogels as a pH-sensitive matrix to deliver methotrexate (MTX) to colon. The primed Gel/PVA hydrogels were subjected to evaluation for swelling behavior, diffusion coefficient, sol-gel characteristic and porosity using an acidic (pH 1.2) and phosphate...

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Detalles Bibliográficos
Autores principales: Akhlaq, Muhammad, Azad, Abul Kalam, Ullah, Inam, Nawaz, Asif, Safdar, Muhammad, Bhattacharya, Tanima, Uddin, A. B. M. Helal, Abbas, Syed Atif, Mathews, Allan, Kundu, Sukalyan Kumar, Miret, Mireia Mallandrich, Murthy, H. C. Ananda, Nagaswarupa, H. P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8309343/
https://www.ncbi.nlm.nih.gov/pubmed/34301057
http://dx.doi.org/10.3390/polym13142300

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8309343/
https://www.ncbi.nlm.nih.gov/pubmed/34301057
http://dx.doi.org/10.3390/polym13142300

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