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A Randomized Controlled Trial of Local Delivery of a Rho Inhibitor (VX-210) in Patients with Acute Traumatic Cervical Spinal Cord Injury

Acute traumatic spinal cord injury (SCI) can result in severe, lifelong neurological deficits. After SCI, Rho activation contributes to collapse of axonal growth cones, failure of axonal regeneration, and neuronal loss. This randomized, double-blind, placebo-controlled phase 2b/3 study evaluated the...

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Detalles Bibliográficos
Autores principales: Fehlings, Michael G., Chen, Yang, Aarabi, Bizhan, Ahmad, Faiz, Anderson, Kim D., Dumont, Travis, Fourney, Daryl R., Harrop, James S., Kim, Kee D., Kwon, Brian K., Lingam, Hari K., Rizzo, Marco, Shih, Ludy C., Tsai, Eve C., Vaccaro, Alexander, McKerracher, Lisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc., publishers 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8309435/
https://www.ncbi.nlm.nih.gov/pubmed/33559524
http://dx.doi.org/10.1089/neu.2020.7096