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A Randomized Controlled Trial of Local Delivery of a Rho Inhibitor (VX-210) in Patients with Acute Traumatic Cervical Spinal Cord Injury
Acute traumatic spinal cord injury (SCI) can result in severe, lifelong neurological deficits. After SCI, Rho activation contributes to collapse of axonal growth cones, failure of axonal regeneration, and neuronal loss. This randomized, double-blind, placebo-controlled phase 2b/3 study evaluated the...
Autores principales: | Fehlings, Michael G., Chen, Yang, Aarabi, Bizhan, Ahmad, Faiz, Anderson, Kim D., Dumont, Travis, Fourney, Daryl R., Harrop, James S., Kim, Kee D., Kwon, Brian K., Lingam, Hari K., Rizzo, Marco, Shih, Ludy C., Tsai, Eve C., Vaccaro, Alexander, McKerracher, Lisa |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Mary Ann Liebert, Inc., publishers
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8309435/ https://www.ncbi.nlm.nih.gov/pubmed/33559524 http://dx.doi.org/10.1089/neu.2020.7096 |
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