A Dual-Sensor-Based Screening System for In Vitro Selection of TDP1 Inhibitors

DNA sensors can be used as robust tools for high-throughput drug screening of small molecules with the potential to inhibit specific enzymes. As enzymes work in complex biological pathways, it is important to screen for both desired and undesired inhibitory effects. We here report a screening system...

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Detalles Bibliográficos
Autores principales: Jakobsen, Ann-Katrine, Keller, Josephine Geertsen, Gonzalez, María, Martin-Encinas, Endika, Palacios, Francisco, Alonso, Concepcion, Knudsen, Birgitta Ruth, Stougaard, Magnus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8309759/
https://www.ncbi.nlm.nih.gov/pubmed/34300575
http://dx.doi.org/10.3390/s21144832

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8309759/
https://www.ncbi.nlm.nih.gov/pubmed/34300575
http://dx.doi.org/10.3390/s21144832

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