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Direct Comparison of the Lowest Effect Concentrations of Mutagenic Reference Substances in Two Ames Test Formats

The Ames assay is the standard assay for identifying DNA-reactive genotoxic substances. Multiple formats are available and the correct choice of an assay protocol is essential for achieving optimal performance, including fit for purpose detection limits and required screening capacity. In the presen...

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Detalles Bibliográficos
Autores principales: Rainer, Bernhard, Pinter, Elisabeth, Prielinger, Lukas, Coppola, Chiara, Marin-Kuan, Maricel, Schilter, Benoit, Apprich, Silvia, Tacker, Manfred
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8309791/
https://www.ncbi.nlm.nih.gov/pubmed/34209992
http://dx.doi.org/10.3390/toxics9070152