Sterigmatocystin, 5-Methoxysterigmatocistin, and Their Combinations are Cytotoxic and Genotoxic to A549 and HepG2 Cells and Provoke Phosphorylation of Chk2, but not FANCD2 Checkpoint Proteins

Sterigmatocystin (STC) and 5-methoxysterigmatocystin (5-M-STC) are structurally related mycotoxins with cytotoxic and genotoxic properties. In the present study, we hypothesized that DNA damage induced by non-cytotoxic concentrations of single and combined mycotoxins could alter the phosphorylation...

Descripción completa

Detalles Bibliográficos
Autores principales: Dabelić, Sanja, Kifer, Domagoj, Jakšić, Daniela, Kopjar, Nevenka, Klarić, Maja Šegvić
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8309960/
https://www.ncbi.nlm.nih.gov/pubmed/34209435
http://dx.doi.org/10.3390/toxins13070464

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8309960/
https://www.ncbi.nlm.nih.gov/pubmed/34209435
http://dx.doi.org/10.3390/toxins13070464

Ejemplares similares