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Sirtuin 3 Restores Synthesis and Secretion of Very Low-Density Lipoproteins in Cow Hepatocytes Challenged with Nonesterified Fatty Acids In Vitro

Fatty liver is closely associated with elevated concentrations of nonesterified fatty acids (NEFA) and a low level of very low-density lipoproteins (VLDL) in blood of dairy cows. High NEFA inhibit the VLDL synthesis and assembly, and cause hepatic triacylglycerol (TAG) deposition. Sirtuin 3 (SIRT3),...

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Detalles Bibliográficos
Autores principales: Xing, Dongmei, Wang, Baogen, Lu, Hong, Peng, Tao, Su, Jianming, Lei, Hongyu, He, Jianhua, Zhou, Yingfang, Liu, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8310004/
https://www.ncbi.nlm.nih.gov/pubmed/34208809
http://dx.doi.org/10.3390/vetsci8070121