Mutation E48K in PB1 Polymerase Subunit Improves Stability of a Candidate Live Attenuated Influenza B Virus Vaccine

Influenza B virus (IBV) is a major respiratory pathogen of humans, particularly in the elderly and children, and vaccines are the most effective way to control it. In previous work, incorporation of two mutations (E580G, S660A) along with the addition of an HA epitope tag in the PB1 segment of B/Bri...

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Detalles Bibliográficos
Autores principales: Mo, Jongsuk, Cardenas-Garcia, Stivalis, Santos, Jefferson J. S., Ferreri, Lucas M., Cáceres, C. Joaquín, Geiger, Ginger, Perez, Daniel R., Rajao, Daniela S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8310045/
https://www.ncbi.nlm.nih.gov/pubmed/34358217
http://dx.doi.org/10.3390/vaccines9070800

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8310045/
https://www.ncbi.nlm.nih.gov/pubmed/34358217
http://dx.doi.org/10.3390/vaccines9070800

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