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Mutation E48K in PB1 Polymerase Subunit Improves Stability of a Candidate Live Attenuated Influenza B Virus Vaccine
Influenza B virus (IBV) is a major respiratory pathogen of humans, particularly in the elderly and children, and vaccines are the most effective way to control it. In previous work, incorporation of two mutations (E580G, S660A) along with the addition of an HA epitope tag in the PB1 segment of B/Bri...
Autores principales: | Mo, Jongsuk, Cardenas-Garcia, Stivalis, Santos, Jefferson J. S., Ferreri, Lucas M., Cáceres, C. Joaquín, Geiger, Ginger, Perez, Daniel R., Rajao, Daniela S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8310045/ https://www.ncbi.nlm.nih.gov/pubmed/34358217 http://dx.doi.org/10.3390/vaccines9070800 |
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