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Development of a Novel Live Attenuated Influenza A Virus Vaccine Encoding the IgA-Inducing Protein
Live attenuated influenza virus (LAIV) vaccines elicit a combination of systemic and mucosal immunity by mimicking a natural infection. To further enhance protective mucosal responses, we incorporated the gene encoding the IgA-inducing protein (IGIP) into the LAIV genomes of the cold-adapted A/Lenin...
Autores principales: | , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8310050/ https://www.ncbi.nlm.nih.gov/pubmed/34198994 http://dx.doi.org/10.3390/vaccines9070703 |