Huntingtin and Its Role in Mechanisms of RNA-Mediated Toxicity

Huntington’s disease (HD) is caused by a CAG-repeat expansion mutation in the Huntingtin (HTT) gene. It is characterized by progressive psychiatric and neurological symptoms in combination with a progressive movement disorder. Despite the ubiquitous expression of HTT, pathological changes occur quit...

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Detalles Bibliográficos
Autores principales: Heinz, Annika, Nabariya, Deepti Kailash, Krauss, Sybille
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8310054/
https://www.ncbi.nlm.nih.gov/pubmed/34357961
http://dx.doi.org/10.3390/toxins13070487

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8310054/
https://www.ncbi.nlm.nih.gov/pubmed/34357961
http://dx.doi.org/10.3390/toxins13070487

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