Improved Activity against Acute Myeloid Leukemia with Chimeric Antigen Receptor (CAR)-NK-92 Cells Designed to Target CD123

Anti-cancer activity can be improved by engineering immune cells to express chimeric antigen receptors (CARs) that recognize tumor-associated antigens. Retroviral vector gene transfer strategies allow stable and durable transgene expression. Here, we used alpharetroviral vectors to modify NK-92 cell...

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Detalles Bibliográficos
Autores principales: Morgan, Michael A., Kloos, Arnold, Lenz, Daniela, Kattre, Nadine, Nowak, Juliette, Bentele, Marco, Keisker, Maximilian, Dahlke, Julia, Zimmermann, Katharina, Sauer, Martin, Heuser, Michael, Schambach, Axel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8310147/
https://www.ncbi.nlm.nih.gov/pubmed/34372571
http://dx.doi.org/10.3390/v13071365

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8310147/
https://www.ncbi.nlm.nih.gov/pubmed/34372571
http://dx.doi.org/10.3390/v13071365

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