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Quaternary Interaction of the HIV-1 Envelope Trimer with CD4 and Neutralizing Antibodies

The entry of HIV-1 into host cells is initiated by the interaction of the viral envelope (Env) spike with the CD4 receptor. During this process, the spike undergoes a series of conformational changes that eventually lead to the exposure of the fusion peptide located at the N-terminus of the transmem...

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Detalles Bibliográficos
Autores principales: Liu, Qingbo, Zhang, Peng, Lusso, Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8310203/
https://www.ncbi.nlm.nih.gov/pubmed/34372611
http://dx.doi.org/10.3390/v13071405