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Prevention of CD8 T Cell Deletion during Chronic Viral Infection

During chronic viral infections, CD8 T cells rapidly lose antiviral and immune-stimulatory functions in a sustained program termed exhaustion. In addition to this loss of function, CD8 T cells with the highest affinity for viral antigen can be physically deleted. Consequently, treatments designed to...

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Detalles Bibliográficos
Autores principales: Brooks, David G., Tishon, Antoinette, Oldstone, Michael B. A., McGavern, Dorian B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8310272/
https://www.ncbi.nlm.nih.gov/pubmed/34206262
http://dx.doi.org/10.3390/v13071189