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Prevention of CD8 T Cell Deletion during Chronic Viral Infection

During chronic viral infections, CD8 T cells rapidly lose antiviral and immune-stimulatory functions in a sustained program termed exhaustion. In addition to this loss of function, CD8 T cells with the highest affinity for viral antigen can be physically deleted. Consequently, treatments designed to...

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Detalles Bibliográficos
Autores principales:	Brooks, David G., Tishon, Antoinette, Oldstone, Michael B. A., McGavern, Dorian B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8310272/ https://www.ncbi.nlm.nih.gov/pubmed/34206262 http://dx.doi.org/10.3390/v13071189

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