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Snapshots of a Non-Canonical RdRP in Action

RNA viruses typically encode their own RNA-dependent RNA polymerase (RdRP) to ensure genome replication and transcription. The closed “right hand” architecture of RdRPs encircles seven conserved structural motifs (A to G) that regulate the polymerization activity. The four palm motifs, arranged in t...

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Detalles Bibliográficos
Autores principales: Ferrero, Diego S., Falqui, Michela, Verdaguer, Nuria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8310298/
https://www.ncbi.nlm.nih.gov/pubmed/34203380
http://dx.doi.org/10.3390/v13071260