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The Expression of Hemagglutinin by a Recombinant Newcastle Disease Virus Causes Structural Changes and Alters Innate Immune Sensing

Recombinant Newcastle disease viruses (rNDV) have been used as bivalent vectors for vaccination against multiple economically important avian pathogens. NDV-vectored vaccines expressing the immunogenic H5 hemagglutinin (rNDV-H5) are considered attractive candidates to protect poultry from both highl...

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Detalles Bibliográficos
Autores principales: Ingrao, Fiona, Duchatel, Victoria, Rodil, Isabel Fernandez, Steensels, Mieke, Verleysen, Eveline, Mast, Jan, Lambrecht, Bénédicte
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8310309/
https://www.ncbi.nlm.nih.gov/pubmed/34358174
http://dx.doi.org/10.3390/vaccines9070758