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Human Peptides α-Defensin-1 and -5 Inhibit Pertussis Toxin

Bordetella pertussis causes the severe childhood disease whooping cough, by releasing several toxins, including pertussis toxin (PT) as a major virulence factor. PT is an AB(5)-type toxin, and consists of the enzymatic A-subunit PTS1 and five B-subunits, which facilitate binding to cells and transpo...

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Detalles Bibliográficos
Autores principales: Kling, Carolin, Pulliainen, Arto T., Barth, Holger, Ernst, Katharina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8310310/
https://www.ncbi.nlm.nih.gov/pubmed/34357952
http://dx.doi.org/10.3390/toxins13070480